45 YEAR OLD MALE WITH FEVER AND ALTERED SENSORIUM

19th May 2022

This is an online E log book to discuss our patient's de-identified health data shared after taking his/her/guardian's signed informed consent. 


Here we discuss our individual patient' problems through series of inputs from available global online community of experts with an aim to solve those patient's clinical problems with collective current best evidence based inputs. 


This E log book also reflects my patient-centered online learning portfolio and your valuable inputs on the comment box is welcome."
I've been given this case to solve in an attempt to understand the topic of "patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with a diagnosis and treatment plan.


45 year old male painter by occupation (since 30years),resident at nalgonda came with 
- c/o fever since 1week
- c/o headache since 4days

HISTORY OF PRESENT ILLNESS :
Patient was apparently 15 years back, then he c/o polyuria went to hospital and was diagnosed with DM-II, since then he was started on OHA's and was under control.
- 2 years back, he c/o fever for 1month (on and off) and continous cough associated with sputum for which he went to Govt hospital and diagnosed with pulmonary TB and was given ATT course for 6 months.
- Again after 6 months, sputum samples were retested and turned out to be negative. 
- Since 1 month he c/o cough (dry) for which he went to local hospital and was prescribed some antibiotics, c/o sputum since 2 weeks (greenish, mucoid, not associated with blood). 
- Outside pleural tap was done showing exudative effusion. 
-  c/o fever since 1 week (on and off), resolving on medication, not associated with chills and rigor. 
- c/o headache since 4days in the parieto occipital region. 
- phonophobia +
- No h/o photophobia, nausea, lacrimation, vomiting, decreased appetite. 

PAST HISTORY :
- k/c/o DM-II since 15years and on Tab Glimi M2 and Tab Metformin
- h/o TB 2years ago
- No h/o HTN, asthma, epilepsy

PERSONAL HISTORY : 
He is married and have 3 daughters. 
Diet - mixed
Appetite - normal 
Bowel and bladder movements - regular 
Sleep - adequate
Occasional alcoholic weekly once to twice since 15years
Chronic smoker 3-4 cigarettes /DAY since 16years

DIETARY HISTORY :
Breakfast - 2 chapatis with curry and ragi malt
Lunch - 1cup of rice with pulses and curry 
Dinner - 2 chapatis with curry / 1 cup of rice with pulses and curry
- He consumes meat once in 2-3 weeks
- He consumes 2 eggs /day

FAMILY HISTORY : Not significant

GENERAL EXAMINATION : 
- Patient is irritable
- Pallor +
- No icterus, cyanosis, clubbing, lymphadenopathy and pedal edema

VITALS AT THE TIME OF ADMISSION :
Temp - 101.1 F
PR - 125 bpm
BP - 90/60 mm Hg
RR - 35 cpm 
Spo2 - 98% @ room air
GRBS - 216 mg/dl

SYSTEMIC EXAMINATION :
CVS - S1S2 +
RS - decreased airway entry on right side in infra axillary, infra mamammary ans infrascapular areas
P/A - soft, nontender
CNS - 
Kernig's sign +
Brudzinski's sign +
Power - 5/5 in all 4 limbs
Tone - normal in all 4 limbs
Reflexes :
- Biceps : 2+ (b/l) 
- Triceps : 2+ (b/l) 
- Supinator : 2+ (b/l) 
- Knee : 2+ (b/l) 
- Ankle : 2+ (b/l) 
- Plantar : flexor

INVESTIGATIONS :
HEMOGRAM :

ESR :
CRP :

CUE :
BLOOD UREA :
SERUM CREATININE :
SERUM ELECTROLYTES :
LFT :
SEROLOGY : NEGATIVE

PT AND INR :
APTT :
CHEST X RAY PA VIEW :
ECG : 
URINE PROTEIN/CREATININE RATIO :
- Urine protein : 33
- Urine creatinine : 95
- Ratio : 0.34
URINARY ELECTROLYTES :
- Urinary Na : 214
- Urinary K : 23
- Urinary Cl : 197
LUMBAR PUNCTURE WAS DONE :


MRI BRAIN PLAIN :
USG CHEST :
USG ABDOMEN :
2D ECHO :
MRI BRAIN PLAIN WITH CONTRAST :
HRCT THORAX :
CSF FOR CULTURE AND SENSITIVITY :
SPUTUM FOR CULTURE AND SENSITIVITY:
OPHTHALMOLOGY REFERRAL DONE I/V/O ANY OPTIC DISC CHANGES :
PULMONOLOGY REFERRAL DONE I/V/O X-RAY CHANGES :

OUTSIDE REPORTS :
PROVISIONAL DIAGNOSIS : ? TB MENINGITIS 

TREATMENT :
1. INJ DEXA 8MG IV TID
2. INJ CEFTRIAXONE 2GM IV BD
3. IVF - NS, RL @ 75ML/HR
4. INJ ZOFER 4MG IV TID
5. INJ PAN 40MG IV OD
6. INJ PCM 1GM IV SOS (IF TEMP > 101F)
7. INJ VANCOMYCIN 1GM IV STAT
8. MONITORING VITALS

SOAP NOTES
20/5/2022
DAY 1
S :
No fever spikes

O :
Patient is drowsy
BP - 80/60 mm Hg
PR - 102 bpm
RR - 21 cpm
Spo2 - 98% @ room air
GRBS - 240 mg/dL (8U HAI given)

INVESTIGATIONS :
CSF ANALYSIS :
CELLS - 15 (100% LYMPHOCYTES) 
SUGARS - 118
LDH - 16
PROTEIN - 28
CHLORIDE - 120

A :
? TB MENINGITIS

P :
1. INJ DEXA 8MG IV TID
2. INJ CEFTRIAXONE 2GM IV BD
3. IVF - NS, RL @ 75 ML/HR
4. INJ ZOFER 4MG IV TID
5. INJ PAN 40MG IV OD
6. INJ PCM 1GM IV SOS (IF TEMP >101 F)

SOAP NOTES
21/5/2022
DAY 2
S :
No fever spikes

O :
Patient is drowsy
BP - 100/70 mm Hg
PR - 108bpm
RR - 21 cpm
Spo2 - 98% @ room air
GRBS - 359 mg/DL (8U HAI given)
GRBS TRENDS : 20/5/2022
8am - 240 mg/dL (8U HAI given) 
2pm - 456 mg/dL 
8pm - 351 mg/dL (6U HAI given) 
2am - 342 mg/dL 
8am - 359 mg/dL (8U HAI given) 

CVS - s1s2+
RS - decreased airway entry on right infrascapular, infra axillary and inframammary areas
P/A - soft, nontender
CNS - NAD

INVESTIGATIONS :
HEMOGRAM :

A :
? TB MENINGITIS
? VIRAL MENINGITIS

P :
1. INJ DEXA 8MG IV TID
2. INJ CEFTRIAXONE 2GM IV BD
3. IVF - NS, RL @ 75 ML/HR
4. INJ ZOFER 4MG IV TID
5. INJ PAN 40MG IV OD
6. INJ PCM 1GM IV SOS (IF TEMP >101 F)
7. INJ ACYCLOVIR 1GM IV BD
8. TAB DOLO 650MG PO TID
9. GRBS 6TH HRLY
10. PLAN TO START ATT

SOAP NOTES
22/5/2022
DAY 3
S :
No fever spikes

O :
Patient is c/c/c
BP - 90/60 mm Hg
PR - 72bpm
RR - 21 cpm
Spo2 - 98% @ room air
GRBS - 232 mg/DL (6U HAI given)
GRBS TRENDS : 21/5/2022
8am - 359 mg/dL (8U HAI given) 
2pm - 275 mg/dL (12U HAI given) 
8pm - 160 mg/dL (4U HAI given) 
2am - 185 mg/dL 
8am - 232 mg/dL (6U HAI given) 

CVS - s1s2+
RS - decreased airway entry on right infrascapular, infra axillary and inframammary areas
P/A - soft, nontender
CNS - NAD

INVESTIGATIONS :
HEMOGRAM :
BLOOD UREA :
PHOSPHORUS :
SERUM ELECTROLYTES :
SERUM CREATININE :

A :
? TB MENINGITIS 

P :
1. INJ DEXA 8MG IV TID
2. INJ CEFTRIAXONE 2GM IV BD
3. IVF - NS, RL @ 75 ML/HR
4. INJ ZOFER 4MG IV TID
5. INJ PAN 40MG IV OD
6. INJ PCM 1GM IV SOS (IF TEMP >101 F)
7. TAB ATT 3TABS/DAY
8. TAB DOLO 650MG PO TID
9. GRBS 6TH HRLY

SOAP NOTES
23/5/2022
DAY 4
S :
No fever spikes

O :
Patient is c/c/c
BP - 100/60 mm Hg
PR - 76bpm
RR - 21 cpm
Spo2 - 98% @ room air
GRBS - 184 mg/dL (6U HAI given)
GRBS TRENDS : 22/5/2022
8am - 232 mg/dL (6U HAI given) 
2pm - 320 mg/dL (14U HAI given) 
8pm - 321 mg/dL (6U HAI given) 
2am - 253 mg/dL 
8am - 184 mg/dL (6U HAI given) 

CVS - s1s2+
RS - decreased airway entry on right infrascapular and inframammary areas crepts +
P/A - soft, nontender
CNS - NAD

INVESTIGATIONS :
HEMOGRAM :

A :
? TB MENINGITIS 

P :
1. INJ DEXA 8MG IV TID
2. INJ CEFTRIAXONE 2GM IV BD
3. IVF - NS, RL @ 75 ML/HR
4. INJ ZOFER 4MG IV TID
5. INJ PAN 40MG IV OD
6. INJ PCM 1GM IV SOS (IF TEMP >101 F)
7. TAB ATT 3TABS/DAY
8. TAB DOLO 650MG PO TID
9. GRBS 6TH HRLY

SOAP NOTES
24/5/2022
DAY 5
S :
No fever spikes

O :
Patient is c/c/c
BP - 90/60 mm Hg
PR - 80 bpm
RR - 21 cpm
Spo2 - 98% @ room air
GRBS - 208 mg/dL (6U HAI given)

GRBS TRENDS - 23/5/2022
8am - 184 mg/dL (6U HAI given)
8pm - 492 mg/dL (6U HAI given)
2am - 300 mg/dL
8am - 208 mg/dL (6U HAI given)

FEVER CHART :


CVS - S1S2 +
RS - BAE+
P/A - soft, nontender
CNS - NAD

INVESTIGATIONS :

HEMOGRAM :


A :
? TB MENINGITIS

P :
1. INJ DEXA 8MG IV TID
2. INJ CEFTRIAXONE 2GM IV BD
3. IVF - NS, RL @ 75 ML/HR
4. INJ ZOFER 4MG IV TID
5. INJ PAN 40MG IV OD
6. INJ PCM 1GM IV SOS (IF TEMP >101 F)
7. TAB ATT 3 tabs/DAY
8. TAB DOLO 650MG PO TID
9. TAB BENADON 40MG PO OD
10. GRBS - 6TH HRLY

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